Impact of hypertrophic versus dilated cardiomyopathy on noninvasively determined indices of left ventricular diastolic function

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Myocardial velocity gradient as a noninvasively determined index of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy.

OBJECTIVES We investigated the utility of the peak negative myocardial velocity gradient (MVG) derived from tissue Doppler imaging (TDI) for evaluation of diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM). BACKGROUND Hypertrophic cardiomyopathy is characterized by impaired diastolic function with abnormal stiffness and prolonged relaxation. However, it remains difficult...

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Left ventricular diastolic gradient in hypertrophic cardiomyopathy☆

Systolic left ventricular (LV) gradients and diastolic dysfunction are widely studied in hypertrophic cardiomyopathy (HCM) [1,2], however diastolic gradients have never been described. A patient with HCM, mid-cavity obliteration and apical aneurysm, diagnosed by both 2D echocardiography (Fig. 1, panel A) and cardiac magnetic resonance (Fig. 1, panel B), showed color Doppler aliasing effect at m...

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Effect of hypertrophy on left ventricular diastolic function in patients with hypertrophic cardiomyopathy

BACKGROUND.: Hypertrophic cardiomyopathy (HCM) is characterized by asymmetric LV hypertrophy (LVH) and impairment in diastolic function. We assess the relationship between LVH and invasive indexes of diastolic function. METHODS.: 21 HCM patients underwent cardiac catheterization to assess pulmonary capillary wedge pressure, LV end-diastolic pressure (measured by microtip catheters), and LV vol...

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Effects of verapamil on left ventricular systolic function and diastolic filling in patients with hypertrophic cardiomyopathy.

Verapamil improves exercise capacity in patients with hypertrophic cardiomyopathy (HCM), but its mechanism of action are unknown. We examined the effects of oral verapamil (320-480 mg/day) on resting left ventricular (LV) systolic and diastolic function in patients with HCM. High-temporal-resolution time-activity curves from gated technetium-99m radionuclide angiograms were analyzed before and ...

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Doppler echocardiographic indices of left ventricular diastolic function

The influence of age on six Doppler echocardiographic indices of left ventricular diastolic function was assessed in 86 normal volunteers aged from 20 to 74 years (mean 36). Five of the six indices showed a linear relation with age. Duration of isovolumic relaxation and maximal late diastolic (atrial) flow velocity increased significantly with age (r = 0-34 and r = 0-69, respectively). Converse...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2003

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(03)81366-9